Acute Inflammation Cellular Events _ Margination _ Immunology The predominant cell of acute inflammation is the neutrophil, which is one type of granulocytes. The migration of neutrophils occurs in four stages, including margination, rolling, adhesion and emigration (Figure 1). Margination refers to cells line up against the endothelium. | Dr. Najeeb

Acute Inflammation - Cellular Events - Rolling- Part 1. Neutrophils are the primary inflammatory cells in the early stages of acute inflammation. They are attracted to the site of injury by chemotaxins, which are mediators released into the blood after an injury. Once at the site of injury, neutrophils phagocytose and degrade any microbes or cellular debris. | Dr. Najeeb