Copy Number Variation - How does it work? AskTaqMan #34
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Copy Number Variation - How does it work? AskTaqMan #34
Genotyping single nucleotide polymorphisms, or SNPs, using TaqMan Assays has been very well established. But have you heard about copy number variations? Copy number variation (CNV) is a type of structural variation that occurs when a DNA segment of 1 kb to several megabases in length is present in variable copy numbers compared to a
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This illustration presents the hierarchical scale of genomic variation, highlighting how genetic changes can occur at multiple levels of the genome. At the largest scale, variations may involve entire chromosomes, encompassing tens to hundreds of millions of DNA bases. Moving to a finer resolution, copy number variations (CNVs) represent large segments of DNA that are duplicated or deleted, spanning thousands to millions of bases. At the gene level, sequence differences typically affect a few th
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