Macrophages are central to mechanobiology research: their physical characteristics-stiffness, adhesion, and ECM (extracellular matrix) sensing-are inextricably linked to their phenotypic polarization ...

Immunotherapy has revolutionized cancer treatment, yet response rates remain highly variable across tumor types and individual patients. Increasing evidence ...

The arterial vasculature is the second most frequently calcified structure in the human body after the skeleton. Calcification of the aorta and aortic valves occurs in most individuals in westernized ...

Rotator cuff tears are among the most common and debilitating musculoskeletal injuries, frequently causing chronic pain, reduced shoulder mobility ...

The "Swiss 100" study identified in the blood of centenarians 37 proteins whose profile appears to be linked to slowed aging.

Rotator cuff tears often heal with stiff, dysfunctional scar tissue, limiting recovery. A new study reveals why tendon ...

The healing of the spinal cord depends on carefully timed interactions between injured nerve cells and their surrounding ...

Within contemporary molecular biology, the regulation of tissue growth has emerged as a central theme linking developmental signaling, metabolic balance, and structural adaptation. Among the molecular ...

Together, these findings indicate that astrocytes undergo profound sex- and region-specific adaptations to chronic ethanol, implicating extracellular matrix and glycosaminoglycan remodeling as key ...

Fungal pathogens that live harmlessly on and inside the human body are increasingly defeating the limited arsenal of antifungal drugs, while simultaneously dodging the immune system’s surveillance.