Sickle cell disease—the subject of a new Seminar in The Lancet—is one of the most prevalent and fastest-growing genetic disorders worldwide. Although its true prevalence is difficult to determine ...

Drug delivery researchers have vastly improved the potential of genetic therapies by overcoming the challenge of consistently getting genes and gene-editing tools where they need to be within cells.

Genome editing-based therapies typically aim to treat disease by correcting underlying genetic mutations in patient's cells.

Neurodegenerative diseases affect more than 57 million people globally. The incidence of these diseases, from Alzheimer's to Parkinson's to ALS and beyond, is expected to double every 20 years. Though ...

A DNA test could help match patients with psychiatric medications, potentially reducing the long and frustrating trial-and-error process.

Neurodegenerative diseases affect more than 57 million people globally. The incidence of these diseases, from Alzheimer's to ...

Cancer biology increasingly recognizes that cancer stem cells (CSCs) represent a critical subpopulation within tumors, marked by their self-renewal, ...

For decades, the idea of resetting the biological clock sounded more like speculative fiction than clinical strategy. The discovery of Yamanaka factors by Nobel laureate Shinya Yamanaka, which can ...