Scientists usually study the molecular machinery that controls gene expression from the perspective of a linear, two-dimensional genome—even though DNA and its bound proteins function in three ...

This article explains how diet creates sustained epigenetic changes that affect long-term health, disease risk, aging, and ...

GLP-1s are building a reputation as "wonder drugs." First characterized for their ability to improve insulin release and treat diabetes, the drugs were later found to promote weight loss and improve ...

GLP-1s are building a reputation as "wonder drugs." First characterized for their ability to improve insulin release and treat diabetes, the drugs were later found to promote weight loss and improve ...

Christine Dunham is a leading expert on the ribosome—an elaborate macro-molecular machine that operates like a factory within a cell to manufacture proteins. "The ribosome is really the most ...

A study has traced thousands of conserved regulatory elements back 300 million years, revealing deep principles of plant genome evolution—a discovery that could pave the way for more precise ...

Osaka Metropolitan University researchers revealed that reduced levels of testosterone combined with fructose intake led to a ...

Researchers profiled nearly 7 million individual cells from mice, identifying which cells are most vulnerable to aging and what drives their decline. The resulting atlas could guide efforts to develop ...

Low testosterone and fructose intake increased liver fat in mice. Gut microbiota changes raised intestinal pyruvate levels, promoting lipid buildup in liver cells and suggesting a pathway driving ...

The kick-off signal for puberty begins in the brain. Specifically, in the hypothalamus, where specific neurons release a hormone that activates the hypophysis, at the base of the skull, which then ...

Microglia (immune cells) and the RANK protein are essential for triggering puberty and maintaining fertility in the brain.