Though treatments are available, there is no cure or vaccine from HIV, which impacts about 38 million people worldwide. It's difficult to target the RNA genome of the HIV virus in part because it ...

Many pathogenic viruses require a specific structure to be infectious, and their proteins form that structure in vivo with remarkable fidelity. The dynamical process by which protein conformations are ...

A computational model of the more than 26 million atoms in a DNA-packed viral capsid expands our understanding of virus structure and DNA dynamics, insights that could provide new research avenues and ...

Researchers at the University of Delaware, using supercomputing resources and collaborating with scientists at Indiana University, have gained new understanding of the virus that causes hepatitis B ...

The multiple protein subunits (green, purple and red) of the plant-infecting brome mosaic virus (left) have separate nucleation and growth phases similar to the MS2 bacteria-infecting virus (right).

Researchers have discovered the atomic structure of a powerful "molecular motor" that packages DNA into the head segment of some viruses during their assembly, an essential step in their ability to ...

With up to 2.4 million U.S. cases and over 250 million chronic cases globally, hepatitis B infection persists despite the availability of a vaccine. Vaccines work by immunizing the body against a ...

WEST LAFAYETTE, Ind. - Biologists have determined the three-dimensional structure of an unusual viral enzyme that is required in the assembly of new viruses. The Paramecium bursaria chlorella virus ...

Ancient viral fossils buried in our DNA are offering fresh clues about how today’s respiratory pathogens infect and spread. By tracing the shared architecture between long-extinct retroviruses and ...