Managed Healthcare Executive

VA’s holistic approach for chronic pain beats CBT, study finds

Randomization across six VA health systems (Sept 2020–Jan 2024) assigned 764 veterans with chronic pain to Whole Health, ...
Morning Overview on MSN

Common heart and blood-pressure drugs may quietly lower the risk of dementia, a large study finds

Millions of older adults already take inexpensive blood-pressure pills every day, and a growing body of research suggests ...
The New England Journal of Medicine

Community-Based Cluster-Randomized Trial to Reduce Opioid Overdose Deaths

Evidence-based practices for reducing opioid-related overdose deaths include overdose education and naloxone distribution, the use of medications for the treatment of opioid use disorder, and ...
ascopubs.org

Bayesian Adaptive Randomization: Full of Promise With a Helping of Caution

Poly(ADP-ribose) Polymerase Inhibitor Combinations in First-Line Metastatic Castration-Resistant Prostate Cancer: Increasing Toxicity With Unclear Benefits In the article that accompanies this ...
The New England Journal of Medicine

Prehospital Whole Blood in Traumatic Hemorrhage — A Randomized Controlled Trial

Whole-blood transfusion has recently gained favor in the management of severe hemorrhage; however, data from large clinical trials evaluating its clinical effectiveness and safety are lacking. We ...
ascopubs.org

Olanzapine Plus Triple Antiemetic Therapy for the Prevention of Carboplatin-Induced Nausea and Vomiting: A Randomized, Double-Blind, Placebo-Controlled Phase III Trial

Phase I Trial of GD2.CART Cells Augmented With Constitutive Interleukin-7 Receptor for Treatment of High-Grade Pediatric CNS Tumors Further trials are warranted that evaluate adding a 10 mg dose of ...