Accurate DNA replication is essential for genome maintenance. Two recent reports have uncovered new molecular mechanisms controlling the termination phase of DNA replication in higher eukaryotes and ...

Abstract: To ensure faultless duplication of the entire genome, eukaryotic replication initiates from thousands of replication origins. Replication forks emanating from origins move through the ...

DNA replication is essential to all life, yet many basic mechanisms in that process remain unknown to scientists. The structure of the replisome—a block of proteins responsible for unwinding the DNA ...

Before a cell divides, its DNA is replicated so that each daughter cell inherits the same genetic information. The two copies, known as "sister chromatids," are held together by a ring-shaped protein ...

A team of scientists led by Professor Nick Dixon at the Research School of Chemistry at The Australian National University have cracked one of the great DNA mysteries. For more than 20 years ...

These cartoons show the old "textbook" view of the replisome, left, and the new view, right, revealed by electron micrograph images in the current study. Prior to this study, scientists believed the ...

The total amount of money invested in the project. The total cost includes EU contribution as well as other project costs not covered by EU funding. It is expressed in euros. Amount of money, by way ...

UPTON, NY-The first-ever images of the protein complex that unwinds, splits, and copies double-stranded DNA reveal something rather different from the standard textbook view. The electron microscope ...

Until now, the exact configuration of the replisome, a protein complex that unzips and copies DNA, has been unknown. After taking the first pictures of this complex, researchers were surprised to find ...

DNA replication is essential to all life, yet many basic mechanisms in that process remain unknown to scientists. The structure of the replisome—a block of proteins responsible for unwinding the DNA ...