Cryo-electron tomography (cryo-ET) can provide invaluable insights into subcellular structures in their native environment at molecular resolution. Cryo-focused ion beam (cryo-FIB) has been widely ...

Nucleic acid extraction from biological samples is inherently difficult to execute consistently across different tissue types. Some tissue matrices are fibrous, contained in protective cell walls, or ...

Microscopic images of human tissue are a cornerstone of biomedical research and clinical diagnostics. Yet despite their importance, these images often remain difficult to analyze systematically and to ...

A team of researchers in Germany has frozen adult mouse brain tissue at cryogenic temperatures and, after thawing it, recorded electrical activity that closely resembled normal function. The work, ...