The sliding clamp proliferating cell nuclear antigen (PCNA) has a crucial role as a processivity factor for DNA replication in eukaryotic cells. PCNA provides a central platform for coordinating many ...
Unconnected strands of DNA must be sealed together during genome replication and repair, and a new KAUST-led investigation shows how the fastening enzyme involved gets the job done. By combining ...
The molecular machinery responsible for replicating human DNA has come into sharper focus and deepened understanding of this fundamental biological process and how it can malfunction. An international ...
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