EurekAlert!

Endosomal stress, a newly defined organelle stress, induces inflammation via ubiquitin signaling

Endosomal stress, the aberrant accumulation of K63 ubiquitin chains on dysfunctional endosomes, activates the TAB2/3–TAK1–NF-kB and p62–Keap1–Nrf2 pathways, resulting in the expression of immune and ...
Palm Beach Post

Immun’Âge® Granted Japanese Patent Recognizing Activation of Nrf2, the Body’s Master Cellular Defense Pathway

LOS ANGELES, CA, UNITED STATES, January 27, 2026 /EINPresswire.com/ — Osato Research Institute today announced that Immun’Âge ®, a fermented papaya preparation ...
EurekAlert!

Novel therapeutic strategy: Nrf2 activation in targeting senescence-related changes in chronic obstructive pulmonary disease

• Activation of nuclear factor erythroid 2-related factor 2 (Nrf2) significantly reduces the accumulation of senescent bronchial epithelial cells in chronic obstructive pulmonary disease (COPD) models ...
The Indianapolis Star

Immun’Âge® Granted Japanese Patent Recognizing Activation of Nrf2, the Body’s Master Cellular Defense Pathway

Backed by more than 30 peer-reviewed human clinical studies supporting endogenous antioxidant activity, cellular resilience, and healthy aging LOS ANGELES, CA, UNITED ...