By targeting a malfunction in the mitochondria, these cellular power plants, the researchers achieved remarkable results: restoring many neuron-to-neuron connections in nerve cell models derived from ...

Alzheimer's is a devastating disease that results in memory loss and cognitive decline. It's caused by brain cells dying and the brain itself shrinking from a buildup of proteins. Millions of seniors ...

Our brain is a complex organ. Billions of nerve cells are wired in an intricate network, constantly processing signals, enabling us to recall memories or to move our bodies. Making sense of this ...

The ambitious effort to chart every neuronal connection in the brain—connectomics—has long been held back by slow, expensive, and technically demanding imaging workflows. In this proof-of-concept ...

Age-related memory decline and neurodegenerative diseases like Alzheimer's are often thought of as irreversible. But the brain is not static; neurons continually adjust the strength of their ...

Harvard researchers have mapped and catalogued more than 70,000 synaptic connections from about 2,000 rat neurons, using a silicon chip capable of recording small yet telltale synaptic signals from a ...