When patients undergo general anesthesia, doctors can choose among several drugs. Although each of these drugs acts on neurons in different ways, they all lead to the same result: a disruption of the ...

Although the mechanisms by which anesthetic drugs induce the state of general anesthesia have been considered one of the biggest mysteries of modern medicine and science, new research is deciphering ...

The localized loss of sensation with resultant reduction in pain stimuli is the end result of local anesthesia. This mode of anesthesia is considered to be safer than general anesthesia, because it ...

Nitrous oxide, commonly known as "laughing gas," has been used in anesthesiology practice since the 1800s, but the way it works to create altered states is not well understood. In a study published in ...

Scientists from Scripps Research have shown how anesthetics cause clusters of lipids in the cell membrane to break apart, triggering downstream processes that lead to a loss of consciousness. Share on ...

General anesthetics induce a coma-like state within seconds, allowing patients to be operated on without feeling pain or discomfort. Yet very little is known about how these drugs work. Now research ...

Age, new comorbidities, inflammation, cognitive reserve, and changes in anxiety levels alter drug effects and recovery.

(A) Schematic diagram of the experimental system that detects calcium release from the endoplasmic reticulum by each ryanodine receptor. (B) Isoflurane selectively activates RyR1 (mean ± standard ...

The new approach involve studying the mechanism of anesthetics from the anatomical to the molecular level to sort out the "why" and develop a way to remove pain and allow for live-saving treatments as ...

Mechanical embolectomy performed with general instead of local anesthesia is associated with worse clinical outcomes and poorer survival, according to an article published online March 25, 2014, ahead ...