Two siblings presented with cardiomyopathy, hypertension, arrhythmia, and fibrosis of the left atrium. Each had a homozygous null variant in CORIN, the gene encoding atrial natriuretic peptide ...

A liquid injected into the heart that sets like a gel could one day prevent strokes caused by atrial fibrillation, animal tests suggest.

A left atrial appendage closure is a procedure your doctor may recommend if: you have atrial fibrillation (also known as AF or AFib) or you are not a good candidate for taking blood thinner medication ...

Left atrial appendage occlusion is a generally safe and effective procedure to lower the risk of stroke in people with atrial fibrillation. It closes or blocks off the left atrial appendage of the ...

This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they ...

TTNtv-positive individuals have a 21-fold increased risk of developing DCM compared to TTNtv-negative individuals. Male sex, age, and pre-existing cardiovascular disease are strongly associated with ...

Mitral regurgitation (MR) is a serious heart condition that often requires corrective surgery. It is characterized by the backflow or "regurgitation" of blood from the heart's left ventricle into the ...

A significant percentage of affected patients were observed to have dilated atria and left ventricular hypertrophy. Ingestion of polyethylene glycol (PEG)-based solutions for bowel preparation prior ...

AFTX-201 uses a proprietary capsid to deliver a human BAG3 transgene, aiming to restore cardiac function with lower doses than conventional gene therapies.

Objective: To obtain the derived parameter left atrial stiffness index (LASI) using two-dimensional speckle tracking imaging (2D-STI) and evaluate the diagnostic value o ...