Stable isotope-labeled internal standards are widely used in laboratory-developed clinical mass spectrometry tests. An equal amount of these internal standards is added to all samples in a batch, ...
High-performance liquid chromatography (HPLC) or ultra-high-performance liquid chromatography (UHPLC) serves as the front end of the analysis, reducing sample complexity before mass detection.
The success of any large-scale proteomics study is fundamentally determined at the sample preparation stage, which serves as the critical bridge between the biological system and the analytical ...
Figure 1. A schematic representation of a lipid nanoparticle encapsulating mRNA. As this new form of biotechnology makes a leap of progress, so too do the analytical approaches supporting its ...
The quality of data derived from MS can be enhanced by imposing a parameter called selected ion monitoring (SIM), which is highly sensitive and allows quantitative analysis that circumvents effects of ...
Liquid chromatography - mass spectrometry (LC-MS) combines two approaches to separate and identify molecules or compounds present in a sample. High performance liquid chromatography (HPLC) separates ...
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