According to a team of researchers at Baylor College of Medicine, Tongji University and collaborating institutions, weaning ...

Researchers at Baylor College of Medicine, the University of Michigan and collaborating institutions have discovered that inflammation in the gut leaves long-term marks on intestinal stem cells (ISCs) ...

According to a team of researchers at Baylor College of Medicine, Tongji University and collaborating institutions, weaning ...

A recent study comparing young and aged mouse intestinal tissues revealed a delicate balance between IFN-γ signaling and ERK/MAPK signaling as crucial for maintaining the intestinal stem cell ...

In a key advance for regenerative medicine and gut health, scientists from Duke-NUS Medical School and Nanyang Technological University, Singapore (NTU Singapore) have uncovered a precise and ...

A recent study led by Associate Professor Takuya Yamamoto and Researcher May Nakajima-Koyama has revealed that maintaining a delicate balance between interferon-gamma (IFN-γ) and extracellular ...

Experiments using mouse models revealed that aging alters the balance of commensal (or helpful) microbes in the gut. These ...

Image Caption: The signaling pathways involved in the intestinal stem cell niche and cell fate determination. Genes & Diseases publishes rigorously peer-reviewed and high quality original articles and ...

The interplay between the circadian clock, intestinal stem cell niche, and epithelial cell fate is shaping our understanding of how gut homeostasis and cellular regeneration are regulated. Recent ...

Drosophila melanogaster has long served as a powerful model for dissecting the principles of tissue homeostasis and regeneration. Within the adult midgut, intestinal stem cells (ISCs) perform the ...

Researchers have discovered that inflammation in the gut leaves long-term marks on intestinal stem cells (ISCs) that reduce their ability to heal the intestine, even after inflammation has receded.