The mechanism of skeletal muscle contraction is a process that relies on calcium signaling. However, the physiological role of calcium-induced calcium release (CICR) through the ryanodine receptor ...
Researchers engineered mice with a mutation (E3896A) in the RyR1 calcium-binding site, eliminating calcium-induced calcium release (CICR) without affecting depolarization-induced calcium release. The ...
Since statins first came to market in the late 1980s, muscle aches, weakness, and fatigue have driven many patients to ...
A research team has found that specific immune cells can connect with muscle fibers in a lightning-fast, neuron-like way to promote healing. These cells deliver quick pulses of calcium, triggering ...