The Noelin family of secreted proteins bind to the external portion of AMPA glutamate receptors and stabilize them on the neuronal cellular membrane, a process necessary for transmission of ...

The next time you reach for a memory or make a quick choice, a storm of tiny signals races through your brain. Scientists can usually see only half of that storm. Now, a new engineered protein finally ...

To solve the mysteries of how learning and memory occur, Johns Hopkins Medicine scientists have created a system to track millions of connections among brain cells in mice — all at the same time — ...

Neurons stochastically generated up to eight different versions of a protein regulating neurotransmitter release, which could vary how they communicate with other cells. Neurons are talkers. They each ...

After each neurotransmitter release, MK801, an open-channel blocker that can only block a channel that has been activated, decreases initial current (which has been normalized for wild type and mutant ...

A research team led by Dr. Àlex Bayés, Head of the Molecular Physiology of the Synapse Group at the Institut de Recerca Sant Pau (IR Sant Pau), has achieved what for decades had been an elusive goal: ...

Glutamate is a chemical messenger in the brain that plays a crucial role in learning and memory. It also functions to regulate mood. In this article, we provide a definition of glutamate and explain ...

Learning lots of new information as a baby requires a pool of ready-to-go, immature connections between nerve cells to form memories quickly. Called silent synapses, these connections are inactive ...