The low efficiency of conventional vectors used for genetic medicines often means delivering them at high doses and by suboptimal routes, leading to inflammation, toxic side effects and limited ...

Directed Evolution (DE) is a method developed by Nobel laureate Frances Arnold to improve protein fitness for specific applications. However, DE can be less efficient when mutations show epistatic ...

Breakthrough directed evolution system boosts virus-like particles for safer, more efficient gene editing, offering a powerful tool for next-generation therapeutic innovations. Study: Directed ...

Gene therapy has experienced an increasing number of successful human clinical trials, leading to numerous FDA-approved therapies based on recombinant viruses for rare disease, cancer, and other ...